Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device. Melania Mesas Gómez, Bárbara Molina-Moya, Bárbara Camila de Araújo, Arnau Pallarès-Rusiñol, Jofre Ferrer-Dalmau, Maria Valnice Boldrín Zanoni, José Domínguez, Esther Julian, María Isabel Pividori Gurgo. Sensors and Actuators B: Chemical. Available online 23 December 2023, 135211. In Press, Journal Pre-proof. https://doi.org/10.1016/j.snb.2023.135211
Highlights
- Innovative preconcentration strategy combines magnetic particles and filtration
- One-Step Immunomagnetic Separation and Labeling reduces analysis time
- The user-friendly cartridge design reduces the need for manual intervention
- The handheld device for the electrochemical readout offers portability and on-site testing capabilities
- LOD significantly improved by 103-fold to 5 CFU mL-1, reaching regulatory limits.
